Vector-Borne Transmission of the Zika Virus Asian Genotype in Europe

Autor: Guillaume A. Durand, Géraldine Piorkowski, Laurence Thirion, Laetitia Ninove, Sandra Giron, Christine Zandotti, Jessica Denis, Cyril Badaut, Anna-Bella Failloux, Gilda Grard, Isabelle Leparc-Goffart, Xavier de Lamballerie
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Viruses, Vol 12, Iss 3, p 296 (2020)
Druh dokumentu: article
ISSN: 1999-4915
DOI: 10.3390/v12030296
Popis: Three autochthonous cases of Zika virus occurred in southern France in August 2019. Diagnosis relied on serology and transcription-mediated amplification. Attempts for virus isolation and ZIKV genome RT-PCR detection remained negative. Since the index case was not identified, we addressed the issue of genotyping and geographical origin by performing hemi-nested PCR and sequencing in the Pr gene. Analysis of 16 genotype-specific Single Nucleotides Polymorphisms identified the Asian genotype and suggested a Southeast Asia origin.
Databáze: Directory of Open Access Journals
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