Hands and feet radiologic involvements in systemic sclerosis

Autor: Fatemeh Badiee, Alireza Fatemi, Reza Zahedpasha, Mohammad Hadi Gharib, Mohammadhassan Jokar, Somayeh Livani, Mehrdad Aghaie, Nafiseh Abdolahi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Rheumatology, Vol 7, Iss 1, Pp 1-9 (2023)
Druh dokumentu: article
ISSN: 2520-1026
DOI: 10.1186/s41927-023-00336-9
Popis: Abstract Aim Systemic sclerosis (SSc) is a rare autoimmune disorder characterized by vascular and fibrosing involvement of the skin and internal organs. In this study, we determined the prevalence and characteristics of radiological hands and feet involvements in Iranian SSc patients to identify the associations between clinical features and radiologic findings. Methods 43 SSc patients (41 women and 2 men), with a median age of 44.8 years (ranges 26–70 years) and a mean disease duration of 11.8 years (ranges 2–28 years) were studied in this cross-sectional study. Results 42 patients had radiological changes both in their hands and feet. Only one patient had alteration just in hand. The most frequent changes that we found in hand were Juxta-articular Osteoporosis (93%), Acro-osteolysis (58.2%), and Joint Space Narrowing (55.8%). The prevalence of joint space narrowing or acro-osteolysis was higher in subjects with active skin involvement [modified Rodnan skin score (mRSS) > 14] [16/21 vs. 4/16 for patients with inactive skin involvement (mRSS
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