| Autor: |
Fraihat Safwan M. |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Green Processing and Synthesis, Vol 13, Iss 1, Pp 31-41 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2191-9550 |
| DOI: |
10.1515/gps-2023-0228 |
| Popis: |
The frequent drugs prescribed for type 2 diabetes patients are linagliptin (LNG) and empagliflozin (EMG) in different drug formulations. The objective of this research is to create and validate selective and simple methods to evaluate both medications in their dosage forms. Method A for the assay of LNG is based on the drug oxidation using an iodate/iodide mixture, while Method B involves the determination of EMG using permanganate oxidation. The regression graphs had good linearity in the ranges of 0.25–20 and 0.20–1.5 µg·ml−1 for the two drugs, respectively. The limits of detection were 0.082 and 0.065 µg·ml−1 for LNG and EMG, respectively. The two methods were validated and applied for the assay of the drugs in dosage forms successfully. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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