Mismatch negativity (MMN) latency as a biomarker of amnestic mild cognitive impairment in Chinese rural elders

Autor: Li li Ji, Yuan yuan Zhang, Lane eZhang, Bing eHe, Guo Hua Lu
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Frontiers in Aging Neuroscience, Vol 7 (2015)
Druh dokumentu: article
ISSN: 1663-4365
DOI: 10.3389/fnagi.2015.00022
Popis: The aim was to evaluate the Mismatch Negativity (MMN) component, a correlate of the automatic detection of changes in the acoustic environment, in healthy adults and adults with aMCI. 43 mild amnestic cognitive impairment (aMCI) subjects and 43 healthy Chinese older adults were arranged into experimental group and control group respectively. Their MMN amplitude and latency were measured at the FZ, FCZ and CZ electrode sites under a passive auditory oddball task. The results showed that the latencies obtained from the FZ, FCZ and CZ electrode sites were significantly longer in the aMCI adults than in the control adults (P
Databáze: Directory of Open Access Journals