An Unusual Case of Allergic Reaction to Anakinra in a Patient with Tumor Necrosis Factor Receptor-1 Associated Periodic Syndrome (TRAPS) and Subsequent Canakinumab Treatment

Autor: Marta Mejias Trueba, Marta Alonso Moreno, Noemi Garrido Puñal, Maria Soriano Martinez
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: European Journal of Case Reports in Internal Medicine (2020)
Druh dokumentu: article
ISSN: 2284-2594
DOI: 10.12890/2020_001668
Popis: Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is a rare hereditary systemic autoinflammatory disease (SAID). Treatment is based on corticosteroids, but often requires the addition of a biologic drug (anti-TNF agent, IL-1 receptor antagonist, etc) to achieve symptom control. The addition of the second drug is not clearly defined and must take into account the characteristics and preferences of the patient. We describe a patient with TRAPS and an allergic reaction to anakinra which was difficult to manage clinically while alternative treatment was being identified.
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