Serum laminin in hepatosplenic human schistosomiasis

Autor: E. R. Parise, M. M. B. Leite-Mór, H. Rosa
Jazyk: angličtina
Rok vydání: 1992
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 87, Pp 127-128 (1992)
Druh dokumentu: article
ISSN: 0074-0276
1678-8060
DOI: 10.1590/S0074-02761992000800018
Popis: Serum laminin level was measured in chronic schistosomiasis. A significant increase in the mean serum laminin levels was observed in patients with hepatosplenic (HS) schistosomiasis (2,57 ± 0,83U/ml), as compared to those in patients with the hepatointestinal (HI) form of the disease (1,38 ± 0,45-U/ml) and in the control group (1,15 ± 0,31 U/ml). In the HS patients there was a significant direct relatiom between serum laminin and percutaneous splenic pulp pressure (r = 0,68). These findigs are compatible with an increased production of lamin in hepatosplenic schistosomiasis with may be related to the observed enlarged liver and spleen basement membranes in such disease.
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