Analysis of macular blood flow changes in thyroid associated ophthalmopathy

Autor: Xiaohan Zhang, Wangyuan Liu, Zhaode Zhang, Jinhui Dai, Jinfeng Zhang, Lingli Lin
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Ophthalmology, Vol 22, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 1471-2415
DOI: 10.1186/s12886-022-02716-0
Popis: Abstract Background To evaluate the changes in macular superficial retinal vessel density and their relation with visual acuity in thyroid-associated ophthalmopathy (TAO) patients with different severity. Methods This cross-sectional observational study included 70 TAO patients and 70 healthy controls. Only data from the right eyes were analyzed. TAO patients were divided into 7 subgroups according to the NOSPECS score. Foveal avascular zone (FAZ), vascular density (VD), and perfusion density (PD) of macular 1 mm diameter and 6 mm diameter areas were measured by optical coherence tomography angiography (OCTA). Results In TAO patients, significant increases were found in macular and foveal vascular densities (FVD) and perfusion densities (FPD) while a significant decrease was found in the FAZ area when compared with the control group (p
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