Mortality rates and risk factors in 1412 Japanese patients with decompensated hepatitis C virus-related cirrhosis: a retrospective long-term cohort study

Autor:	Shunichiro Fujiyama, Norio Akuta, Hitomi Sezaki, Mariko Kobayashi, Yusuke Kawamura, Tetsuya Hosaka, Masahiro Kobayashi, Satoshi Saitoh, Fumitaka Suzuki, Yoshiyuki Suzuki, Yasuji Arase, Kenji Ikeda, Hiromitsu Kumada
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Decompensated HCV-related cirrhosis Hepatocellular carcinoma Long-term Mortality Natural history Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	BMC Gastroenterology, Vol 21, Iss 1, Pp 1-10 (2021)
Druh dokumentu:	article
ISSN:	1471-230X
DOI:	10.1186/s12876-021-01770-0
Popis:	Abstract Background Hepatitis C virus is the leading cause of liver cirrhosis and hepatocellular carcinoma in Japan. We aimed to examine the long-term (> 20 years) mortality and hepatocellular carcinoma rates and associated risk factors in 1412 Japanese patients with decompensated hepatitis C virus-related cirrhosis (Child–Pugh B or C). Methods Cumulative survival and hepatocellular carcinoma rates were determined using Kaplan–Meier analysis. Independent risk factors were identified by multivariate analysis. A two-tailed P-value of
Databáze:	Directory of Open Access Journals
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