Seizure Induced by Extended-Release Bupropion Used for Smoking Cessation at Early Term and Therapeutic Dose

Autor: Zeynep ÖZÖZEN AYAS, Aslı AKSOY GÜNDOĞDU
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Archives of Epilepsy, Vol 24, Iss 3, Pp 127-129 (2018)
Druh dokumentu: article
ISSN: 2792-0550
DOI: 10.14744/epilepsi.2018.04796
Popis: Bupropion inhibits reuptakes of dopamine and noradrenaline. Since it is also a nicotine receptor antagonist, it acts as a drug used for smoking cessation. Bupropion is commonly preferred because of no side effects on weight, sexual function, and the lack of sedative effect. Immediate and sustained-release bupropion forms may trigger seizure activity. In the present article, we report a case of a 30-year-old man presenting with generalized tonic clonic seizures induced by extended-release bupropion. We also emphasized that extended-release bupropion, which is commonly used for smoking cessation therapy, may cause seizure at early term and therapeutic dose.
Databáze: Directory of Open Access Journals