Goal-Directed Fluid Therapy Using Normal Saline versus Ringer's Lactate in Pediatric Neurosurgical Patients: A Randomized Controlled Trial

Autor: Aparna Depuru, Kirandeep Kaur, Kiran Jangra, Navneet Singla, Hemant Bhagat, Shiv Lal Soni, Nidhi B. Panda, Vinitha Narayan, Anuj Prabhakar
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Neuroanaesthesiology and Critical Care, Vol 11, Iss 01, Pp 018-025 (2024)
Druh dokumentu: article
ISSN: 2348-0548
2348-926X
DOI: 10.1055/s-0043-1778076
Popis: Background Ringer's lactate (RL) and 0.9% sodium chloride (NS) are used intraoperatively in pediatric surgical patients. The fluid of choice in pediatric neurosurgical patients is still under research. Hence, we compared NS and RL intraoperatively with a primary objective of measuring the absolute difference in serum chloride concentrations (ΔCl-) after surgery from baseline. Secondary objectives included changes in other electrolytes, osmolarity, pH, creatinine, brain relaxation score (BRS), and neurological outcome at discharge using a modified Rankin scale (mRS).
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