| Autor: |
Hakuto Kageyama, Rungaroon Waditee-Sirisattha |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
AIMS Molecular Science, Vol 10, Iss 4, Pp 295-310 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2372-0301 |
| DOI: |
10.3934/molsci.2023017?viewType=HTML |
| Popis: |
Mycosporine-like amino acids (MAAs) are ultraviolet (UV)-absorbing substances biosynthesized by specific algae and cyanobacteria. MAAs are thought to contribute to protection against UV radiation in the cells of MAA producers. In addition, it has been reported that MAAs exhibit distinct physiological activities including antioxidant activity, suggesting that they are multifunctional substances. Due to their useful activities, MAAs are also expected to have industrial applications such as skin care, cosmetics and pharmaceuticals. We have focused on mycosporine-2-glycine (M2G), a sole MAA biosynthesized by the halotolerant cyanobacterium Halothece sp. PCC7418 (hereafter referred to as Halothece). In cyanobacteria, M2G is a rare MAA that has been detected only in halotolerant strains. We have elucidated the biosynthetic pathway of M2G in Halothece and partially revealed its intracellular dynamics. In addition, we have reported several important bioactivities of M2G from the viewpoints of skin care and antiaging. This review systematically summarizes the distribution, biosynthetic regulation, and bioactivities of M2G. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
|
Nepřihlášeným uživatelům se plný text nezobrazuje |
K zobrazení výsledku je třeba se přihlásit.
|
