Bioactivity and Thermal Stability of Collagen–Chitosan Containing Lemongrass Essential Oil for Potential Medical Applications

Autor:	Maria Râpă, Traian Zaharescu, Laura Mihaela Stefan, Carmen Gaidău, Ioana Stănculescu, Rodica Roxana Constantinescu, Maria Stanca
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	collagen hydrolysate chitosan lemongrass essential oil gamma irradiation chemiluminescence radical scavenging activity Organic chemistry QD241-441
Zdroj:	Polymers, Vol 14, Iss 18, p 3884 (2022)
Druh dokumentu:	article
ISSN:	2073-4360
DOI:	10.3390/polym14183884
Popis:	Bioactive collagen–chitosan–lemongrass (COL–CS–LG) membranes were prepared by casting method and analyzed for potential biomedical applications. For COL–CS–LG membranes, LG essential oil release, antioxidant properties, in vitro cytotoxicity and antimicrobial assessments were conducted, as well as free radical determination after gamma irradiation by chemiluminescence, and structural characteristics analysis through Attenuated Total Reflection–Fourier Transform Infrared Spectroscopy (ATR–FTIR) and Differential Scanning Calorimetry (DSC). The evaluation of non-isothermal chemiluminescence after gamma radiation exposure to COL–CS–LG membranes revealed a slowing down of the oxidation process at temperatures exceeding 200 °C, in correlation with antioxidant activity. Antimicrobial properties and minimum inhibitory concentrations were found to be in correlation with cytotoxicity limits, offering the optimum composition for designing new biomaterials.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e852a237b2ef49088b40e20c1e66d744 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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