Increased neutrophil lymphocyte ratio and platelet lymphocyte ratio in malignant parotid tumors

Autor: İhsan Kuzucu, İsmail Güler, Rauf Oğuzhan Kum, Deniz Baklacı, Müge Özcan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Brazilian Journal of Otorhinolaryngology, Vol 86, Iss 1, Pp 105-110 (2020)
Druh dokumentu: article
ISSN: 1808-8694
DOI: 10.1016/j.bjorl.2019.02.009
Popis: Introduction: Recently it has been reported that a high preoperative neutrophil–lymphocyte ratio and platelet–lymphocyte ratio may be related to increased recurrence risk, tumor aggressiveness, and worsened prognosis in various malignancies. Objective: The objective of this research is to explore whether neutrophil–lymphocyte ratio and platelet–lymphocyte ratio in parotid tumors may or may not be used as a cancer marker. Methods: This retrospective research has been conducted on a total of 228 patients consisting of 83 healthy persons and 145 patients with a mass in the parotid gland, who applied to a tertiary referral center and underwent surgery. Patients have been divided into two groups by their histopathological findings as malignant or benign parotid tumor. A third group consisting of healthy people has been defined as the control group. Also the malignant parotid tumor group has been divided into two subgroups as early stage and advanced stage. The groups have been compared in terms of neutrophil–lymphocyte ratio, platelet–lymphocyte ratio and other laboratory data. Results: The average neutrophil–lymphocyte ratio values of malignant parotid tumor, benign parotid tumor, healthy control groups were 2.51, 2.01, 1.79 respectively and the difference was statistically significant (p
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