Ct, IL-18 polymorphism, and laboratory biomarkers for predicting chemosensory dysfunctions and mortality in COVID-19

Autor: Shukur Wasman Smail, Esmaeil Babaei, Kawa Amin
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Future Science OA, Vol 9, Iss 2 (2023)
Druh dokumentu: article
ISSN: 2056-5623
DOI: 10.2144/fsoa-2022-0082
Popis: Aim: Patients with COVID-19 often experience chemosensory dysfunction. This research intends to uncover the association of RT-PCR Ct value with chemosensory dysfunctions and SpO2. This study also aims to investigate Ct, SpO2, CRP, D-dimer, and -607 IL-18 T/G polymorphism in order to find out predictors of chemosensory dysfunctions and mortality. Materials & methods: This study included 120 COVID-19 patients, of which 54 were mild, 40 were severe and 26 were critical. CRP, D-dimer, RT-PCR, and IL-18 polymorphism were evaluated. Results & conclusion: Low Ct was associated with SpO2 dropping and chemosensory dysfunctions. IL-18 T/G polymorphism did not show an association with COVID-19 mortality; conversely, age, BMI, D-dimer and Ct values did.
Databáze: Directory of Open Access Journals