Comparison of ramosetron's and ondansetron's preventive anti-emetic effects in highly susceptible patients undergoing abdominal hysterectomy

Autor: Jae-Woo Lee, Hye Jin Park, Juyoun Choi, So Jin Park, Hyoseok Kang, Eu-Gene Kim
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Korean Journal of Anesthesiology, Vol 61, Iss 6, Pp 488-492 (2011)
Druh dokumentu: article
ISSN: 2005-6419
2005-7563
DOI: 10.4097/kjae.2011.61.6.488
Popis: BackgroundThis study compared the preventive effects of ramosetron and ondansetron on postoperative nausea and vomiting (PONV) in highly susceptible patients undergoing abdominal hysterectomy.MethodsIn a prospective, randomized, double-blinded study, a total of 120 highly susceptible women (nonsmokers, those receiving opioid-based IV patient-controlled analgesia [PCA]) undergoing abdominal hysterectomy were included in the study. Patients were divided into 2 groups and each group received either 0.3 mg of ramosetron or 4 mg of ondansetron, IV. All patients received fentanyl-based IV PCA during the 48 h postoperative periods. The incidences of PONV and side effects of 5-HT3 antagonists (headache and dizziness) were assessed at 3 intervals (
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