Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component

Autor: Shrijeet Chakraborti, Hema Kini, Santosh Rai, Ashvini Kumar
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Medical Journal of Dr. D.Y. Patil University, Vol 8, Iss 3, Pp 407-410 (2015)
Druh dokumentu: article
ISSN: 0975-2870
DOI: 10.4103/0975-2870.150498
Popis: Mixed germ cell tumors (GCTs) are aggressive tumors owing to poor response to therapy, frequent recurrence and metastasis. We present here a case of 29-year-old male with recurrent metastatic mixed GCT in the left parietal lobe, with right testicular primary. Interestingly, the recurrent tumor exhibited a seminomatous component, in addition to yolk sac tumor and embryonal carcinoma. The patient was treated with surgery, cranial radiotherapy and cisplatin-based chemotherapy. The metastatic intracranial tumor recurred twice and the patient died 18 months after the first appearance of central nervous system metastasis.
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