Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru

Autor:	Miguel Angel Aguilar-Luis, Fernando Palacios-Cuervo, Fátima Espinal-Reyes, Andrea Calderón-Rivera, Saúl Levy-Blitchtein, Carlos Palomares-Reyes, Wilmer Silva-Caso, Victor Zavaleta-Gavidia, Jorge Bazán-Mayra, Angela Cornejo-Tapia, Juana del Valle-Mendoza, Luis J. del Valle
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Helicobacter pylori PCR Clarithromycin Gastric disease Peptic ulcer disease Medicine Biology (General) QH301-705.5 Science (General) Q1-390
Zdroj:	BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Druh dokumentu:	article
ISSN:	1756-0500
DOI:	10.1186/s13104-018-3919-z
Popis:	Abstract Objective The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). Results Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G–A2143G (28.6%).
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/84ddd5ee71fd4ba582f3cd5dfd83390b Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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