Effect of spirulina supplementation on selected components of Th1/Th2 balance in rowers

Autor: Artur Juszkiewicz, Piotr Basta, Jerzy Trzeciak, Elżbieta Petriczko, Mirosława Cieślicka, Anna Skarpańska-Stejnborn
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Food and Agricultural Immunology, Vol 30, Iss 1, Pp 178-189 (2019)
Druh dokumentu: article
ISSN: 0954-0105
1465-3443
09540105
DOI: 10.1080/09540105.2018.1561830
Popis: The aim of the study was to analyse the effect of spirulina supplementation on blood levels of selected cytokines in athletes exposed to strenuous physical exercise, with emphasis on Th1/Th2 balance. The double-blind study included 19 members of the Polish Rowing Team. The subjects were randomly assigned to the supplemented group, receiving 1500 mg of spirulina extract for 6 weeks, or to the placebo group. After the supplementation, athletes from the placebo group showed a significant post-recovery reduction of IL-2 level, which contributed to a significant decrease in IL-2/IL-4 and IL-2/IL-10 ratios at the end of a 24-h recovery period. Although this study did not demonstrate significant post-supplementation changes in Th1 and Th2 cytokine levels, the lack of a shift in Th1/Th2 balance toward Th2-type response in the supplemented group implies that some constituents of spirulina may exert an indirect beneficial effect on athletes’ immunity.
Databáze: Directory of Open Access Journals