Autor: |
Ding-Guo Huang, Jian-Long Zheng, Guo-Qiao Lin, Wei-Qi Chen |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
Guoji Yanke Zazhi, Vol 18, Iss 9, Pp 1692-1695 (2018) |
Druh dokumentu: |
article |
ISSN: |
1672-5123 |
DOI: |
10.3980/j.issn.1672-5123.2018.9.31 |
Popis: |
AIM: To evaluate the early changes of retinal function in patients with wet age-related macular degeneration(ARMD)after intravitreal Conbercept treatment by multifocal electroretinography(mfERG). METHODS: Wet ARMD patients diagnosed by fundus fluorescein angiography and received intravitreal injection of Conbercept(0.05mL/0.5mg)were included. Best corrected visual acuity(BCVA), incubation of N1, P1 and amplitude of P1 in mfERG test were recorded before and 1mo after treatment. RESULTS: Twenty patients(20 eyes)were enrolled in total. The mean BCVA was 0.80±0.48 LogMAR at baseline and improved to 0.65±0.50 LogMAR after treatment(P2 to 53.81±20.41nV/deg2(P=0.006). The change in visual acuity was positively correlated with the change in P1 amplitude density of Ring 1(r=-0.776, PCONCLUSION: Intravitreal conbercept injection can improve the central retinal function of wet ARMD patients in the short term. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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