| Autor: |
Débora Cardozo Bonfim Carbone, Lourdes Zélia Garcia Zanoni, Fernanda Zanoni Cônsolo, Simone Camargo Sanches, Vanessa Quadros dos Reis, Karla de Toledo Candido Muller, Cristiano Marcelo Espinola Carvalho, Maria Cláudia Silva |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Revista do Instituto de Medicina Tropical de São Paulo, Vol 60, Iss 0 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1678-9946 |
| DOI: |
10.1590/s1678-9946201860050 |
| Popis: |
ABSTRACT Leishmaniasis is a disease complex with various clinical symptoms caused by different species of parasites of the genus Leishmania. The visceral form of the disease, characterized by severe symptoms is fatal, if not treated. The high toxicity of current antileishmanial drugs and the need for long-term treatment make the therapy complicated, especially in a large number of infected children. Hence, the search for new therapies must be intensified. Oral administration of the trace element zinc has been considered in alternative treatments against different clinical forms of leishmaniasis. This study revealed that the administration of zinc in children with visceral leishmaniasis, during treatment with amphotericin B or glucantime, accelerates the regression of the spleen enlargement without interfering with the recovery of hematological parameters. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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