Prognostic significance of preoperative plasma D-dimer level in patients with surgically resected clinical stage I non-small cell lung cancer: a retrospective cohort study
| Autor: | Kaoru Kaseda, Keisuke Asakura, Akio Kazama, Yukihiko Ozawa |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Journal of Cardiothoracic Surgery, Vol 12, Iss 1, Pp 1-8 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1749-8090 76475727 |
| DOI: | 10.1186/s13019-017-0676-3 |
| Popis: | Abstract Background Plasma D-dimer level, a marker of hypercoagulation, has been reported to be associated with survival in several types of cancers. The present study aimed to evaluate the prognostic significance of preoperative D-dimer levels in patients with surgically resected clinical stage I non-small cell lung cancer (NSCLC). Methods Participants comprised 237 patients with surgically resected clinical stage I NSCLC. In addition to factors such as age, sex, and smoking status, the association between preoperative D-dimer level and survival was explored. Results Patients were divided into two groups according to D-dimer level: Group A, ≤ 1.0 μg/ml (n = 170); and Group B, > 1.0 μg/ml (n = 67). The 5-year recurrence-free survival rate was 81.6% for Group A and 66.6% for Group B (p |
| Databáze: | Directory of Open Access Journals |
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