Topical bromfenac for post-cataract extraction: A systematic review and pooled analysis
| Autor: | M-Z Zhai, H-H Wu, J-J Li, L-P Jiang, Z-S Gao, W Hu, Y Liu, Y-T Wang |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | European Journal of Inflammation, Vol 13 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1721-727X 1721727X |
| DOI: | 10.1177/1721727X15601732 |
| Popis: | Bromfenac, a promising ophthalmic non-steroidal anti-inflammatory drug, has been used once daily for postoperative ocular inflammation and pain with satisfying efficacy, however, no integrated conclusion on its safety in clinical settings has been drawn. The purpose of this pooled analysis is to investigate the safety and efficacy of once daily bromfenac for ocular inflammation and pain among patients after cataract extraction (CE). MEDLINE, PsycINFO, Scopus, EMBASE, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched from inception to September 2014. Randomized controlled trials (RCTs) that studied topical bromfenac after CE were analyzed. Included studies were systemically reviewed, and effects were summarized using odds ratio (OR) with suitable effect model. Four RCTs involving 2294 participants were included. Topical bromfenac significantly increased the proportion of cleared ocular inflammation (OR, 2.37; 95% confidence interval [CI], 1.83–3.07; P |
| Databáze: | Directory of Open Access Journals |
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