Riboswitches, from cognition to transformation

Autor: Jingdong Xu, Junyuan Hou, Mengnan Ding, Zhiwen Wang, Tao Chen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Synthetic and Systems Biotechnology, Vol 8, Iss 3, Pp 357-370 (2023)
Druh dokumentu: article
ISSN: 2405-805X
DOI: 10.1016/j.synbio.2023.05.008
Popis: Riboswitches are functional RNA elements that regulate gene expression by directly detecting metabolites. Twenty years have passed since it was first discovered, researches on riboswitches are becoming increasingly standardized and refined, which could significantly promote people's cognition of RNA function as well. Here, we focus on some representative orphan riboswitches, enumerate the structural and functional transformation and artificial design of riboswitches including the coupling with ribozymes, hoping to attain a comprehensive understanding of riboswitch research.
Databáze: Directory of Open Access Journals