Diffuse Facial Hyperpigmentation as a Presenting Sign of Lupus Erythematosus: Three Cases and Review of the Literature

Autor:	Shir Azrielant, Eran Ellenbogen, Alon Peled, Valentina Zemser-Werner, Liat Samuelov, Eli Sprecher, Mor Pavlovsky
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	hyperpigmentation lupus erythematosus photosensitivity connective tissue disorders Dermatology RL1-803
Zdroj:	Case Reports in Dermatology, Vol 13, Iss 2, Pp 263-270 (2021)
Druh dokumentu:	article
ISSN:	1662-6567
DOI:	10.1159/000515732
Popis:	Lupus erythematosus (LE) is an autoimmune disorder commonly affecting the skin; cutaneous lesions may indicate systemic involvement, warranting further evaluation. Photosensitivity, which may result in hyperpigmentation, is a well-known feature of the disease. In contrast, the prevalence of primary hyperpigmentation as a presenting sign of LE is not well established. Here, we compare 3 unique cases of diffuse facial hyperpigmentation as the primary manifestation of LE (cutaneous or systemic) and review previously reported cases. Our data highlight the need for considering LE in the differential diagnosis of facial hyperpigmentation and substantiate the importance of this unique lupus variant in early diagnosis and patient evaluation.
Databáze:	Directory of Open Access Journals
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