Evaluation of Mean Platelet Volume in Patients with Pigmented Purpuric Dermatosis

Autor: Anıl Gülsel BAHALI, Dilek BIYIK ÖZKAYA, Fatma Pelin CENGİZ, Nazan EMİROĞLU, Özlem SU, Mehmet Onur KAYA, Nahide ONSUN
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Bezmiâlem Science, Vol 5, Iss 1, Pp 27-29 (2017)
Druh dokumentu: article
ISSN: 2148-2373
DOI: 10.14235/bs.2016.922
Popis: Objective:Pigmented purpuric dermatosis (PPD) is a chronic skin disease characterized by petechial and pigmentary macules. The etiology of the disease remains unknown. Mean platelet volume (MPV) is a marker of platelet (PLT) function and activation. PLTs play important roles in inflammation and innate and adaptive immunity in addition to their roles in hemostasis and thrombosis. In this study, we investigated the possible association between MPV and PPD.Methods:Forty patients with PPD were enrolled in the study. The control group consisted of 64 healthy subjects. The study design was retrospective. The age, gender, and MPV and PLT levels were recorded from patients’ charts. Cases who had received any medicine affecting PLT function and had a concomitant disease were excluded from the study.Results:The mean MPV levels were 9.7±2.1 fl and 8.0±1.1 fl in the patient and control groups, respectively. This difference was significant (p
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