Autor: |
Xiao-Ming Zhang, Denghong Chen, Xiao-Hua Xie, Jun-E Zhang, Yingchun Zeng, Andy SK Cheng |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
|
Zdroj: |
BMC Geriatrics, Vol 21, Iss 1, Pp 1-13 (2021) |
Druh dokumentu: |
article |
ISSN: |
1471-2318 |
DOI: |
10.1186/s12877-021-02276-w |
Popis: |
Abstract Background The evidence of sarcopenia based on CT-scan as an important prognostic factor for critically ill patients has not seen consistent results. To determine the impact of sarcopenia on mortality in critically ill patients, we performed a systematic review and meta-analysis to quantify the association between sarcopenia and mortality. Methods We searched studies from the literature of PubMed, EMBASE, and Cochrane Library from database inception to June 15, 2020. All observational studies exploring the relationship between sarcopenia based on CT-scan and mortality in critically ill patients were included. The search and data analysis were independently conducted by two investigators. A meta-analysis was performed using STATA Version 14.0 software using a fixed-effects model. Results Fourteen studies with a total of 3,249 participants were included in our meta-analysis. The pooled prevalence of sarcopenia among critically ill patients was 41 % (95 % CI:33-49 %). Critically ill patients with sarcopenia in the intensive care unit have an increased risk of mortality compared to critically ill patients without sarcopenia (OR = 2.28, 95 %CI: 1.83–2.83; P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|