Free Radical-Mediated Cell Disruptions in Pregnancy - A Risk Factor for Preeclampsia

Autor: Kausar Aamir, Arfa Azhar, Fatima Abid, Aliya Jafri, Noorulain Qureshi, Sumaira Riffat
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Pakistan Journal of Medicine and Dentistry, Vol 10, Iss 2 (2024)
Druh dokumentu: article
ISSN: 2313-7371
2308-2593
DOI: 10.36283/PJMD10-2/006
Popis: Background: Preeclampsia is a multifactorial disorder leading to complications of pregnancy. Vitamin E as an antioxidant has been proved to suppress the oxidative stress mechanism by interfering with the propagation of lipid radicals. The objective of the study was to probe antioxidant nutrient profiles in patients with a risk factor for preeclampsia. Methods: This study was done in the Obstetric Outpatient Department of Jinnah Postgraduate Medical Centre, Karachi from 2019-2019. The study group comprised 110 patients divided into three groups as Group A: n=40 Normotensive patients, Group B: n=40 Mild hypertensive (test group I), Group C: n=30 Severe hypertensive (test group II). SPSS version 21 was used for data analysis with p-value 0.05 considered as statistically significant. Results: Plasma ascorbic acid levels stayed considerably (p
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