Rare case of Richter’s syndrome localization in liver and thyroid of a patient with a chronic lymphocytic leukemia (CLL) – Case report and literature

Autor: Ewa Wąsik-Szczepanek, Agnieszka Szymczyk, Dariusz Szczepanek, Ewelina Grywalska, Justyna Szumiło, Piotr Trojanowski, Olga Czabak, Marek Hus
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Annals of Agricultural and Environmental Medicine, Vol 27, Iss 1, Pp 160-164 (2020)
Druh dokumentu: article
ISSN: 1232-1966
1898-2263
DOI: 10.26444/aaem/106041
Popis: Richter’s syndrome (RS) is a rare complication in which chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) transforms into a more aggressive type of lymphoma – diffuse large B cell lymphoma (DLBCL), or Hodgkin’s lymphoma (HL). The review describes the clinical case of a patient with CLL and RS diagnosis. A computed tomography (CT) scan of the abdominal cavity detected numerous normodense areas in the liver. Simultaneously, ultrasound examination (USG) of the thyroid revealed the presence of a solid hypoechogenic lump. The material sampled from closed biopsies of liver and thyroid in both cases allowed the diagnosis of diffuse large B cell lymphoma (DLBCL). The liver and the thyroid are particularly rare locations of RS. However, those cases allowed the conclusion that RS may occur even in a very unexpected and less probable location.
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