Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in miceResearch in context

Autor: N. Naganna, Clement Opoku-Temeng, Eun Yong Choi, Elizabeth Larocque, Elizabeth T. Chang, Brandon A. Carter-Cooper, Modi Wang, Sandra E. Torregrosa-Allen, Bennett D. Elzey, Rena G. Lapidus, Herman O. Sintim
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: EBioMedicine, Vol 40, Iss , Pp 231-239 (2019)
Druh dokumentu: article
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2019.01.012
Popis: Background: Acute myeloid leukemia (AML) remains one of the most lethal, rarely cured cancers, despite decades of active development of AML therapeutics. Currently, the 5-year survival of AML patients is about 30% and for elderly patients, the rate drops to
Databáze: Directory of Open Access Journals