DNA-based platform for efficient and precisely targeted bioorthogonal catalysis in living systems

Autor: Yawen You, Qingqing Deng, Yibo Wang, Yanjuan Sang, Guangming Li, Fang Pu, Jinsong Ren, Xiaogang Qu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-29167-x
Popis: Copper-click reaction has been used for a wide range of bio-conjugations but does suffer from toxicity issues. Here, the authors report on the growth of copper nanoparticles on DNA with linked aptamer targeting and demonstrate high catalytic effect and improved application due to targeting and biocompatibility.
Databáze: Directory of Open Access Journals