Current nanocarriers in therapeutic improvement of Andrographolide
Autor: | Van Hong Nguyen, An Hong Nguyen Pham |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Vietnam Journal of Science, Technology and Engineering, Vol 64, Iss 3 (2022) |
Druh dokumentu: | article |
ISSN: | 2525-2461 2615-9937 |
DOI: | 10.31276/VJSTE.64(3).62-68 |
Popis: | Currently, herbs have been investigated for novel bioactivities and improvement of traditional therapeutic effectiveness. Among them, Andrographis paniculata, with the active component Andrographolide, is well recognized as an antiinflammatory, anti-bacterial, anti-cancer, anti-hypertensive, anti-hyperglycaemic, hepatoprotective, and antihyperlipidaemic compound. However, Andrographolide has poor physicochemical properties that limit its medical application. In this review article, nano drug delivery systems including nanovesicles, inorganic nanoparticles, lipidbased nanoparticles, polymeric nanoparticles, nanocrystals, nanoemulsions, and microemulsions, which can deliver Andrographolide through different routes such as oral, injection, or dermal, and their influences in increasing treatment benefits are presented. |
Databáze: | Directory of Open Access Journals |
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