Current nanocarriers in therapeutic improvement of Andrographolide

Autor: Van Hong Nguyen, An Hong Nguyen Pham
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Vietnam Journal of Science, Technology and Engineering, Vol 64, Iss 3 (2022)
Druh dokumentu: article
ISSN: 2525-2461
2615-9937
DOI: 10.31276/VJSTE.64(3).62-68
Popis: Currently, herbs have been investigated for novel bioactivities and improvement of traditional therapeutic effectiveness. Among them, Andrographis paniculata, with the active component Andrographolide, is well recognized as an antiinflammatory, anti-bacterial, anti-cancer, anti-hypertensive, anti-hyperglycaemic, hepatoprotective, and antihyperlipidaemic compound. However, Andrographolide has poor physicochemical properties that limit its medical application. In this review article, nano drug delivery systems including nanovesicles, inorganic nanoparticles, lipidbased nanoparticles, polymeric nanoparticles, nanocrystals, nanoemulsions, and microemulsions, which can deliver Andrographolide through different routes such as oral, injection, or dermal, and their influences in increasing treatment benefits are presented.
Databáze: Directory of Open Access Journals