Association of polymorphism of genes of folate cycle and blood serum content of interleukin-33 in patients with high summary cardiovascular risk on the combined therapy of arterial hypertension
| Autor: | I. I. Chukaeva, А. I. Khachirova, L. V. Gankovskaya, M. V. Khoreva, I. V. Kostomarova |
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| Jazyk: | English<br />Russian<br />Ukrainian |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Patologìâ, Iss 2, Pp 51-54 (2014) |
| Druh dokumentu: | article |
| ISSN: | 2310-1237 2306-8027 |
| DOI: | 10.14739/2310-1237.2014.2.28565 |
| Popis: | Aim. The study of genetic factors of cardiovascular diseases is of great importance, as the screening of major risk factors that cause the development of cardiovascular accidents across the globe does not enable identifying at least half of those who appear to suffer from the diseases in the future. In order to solve this particular problem, an effect of combined therapy of hypertension on the interleukin 33 (IL-33) in patients who appear to be at high risk of developing cardiovascular diseases as well as the presence of polymorphisms of genes of the folate cycle (MTHFR C677T, A1298G, MTR А2756G, MTRR A66G) have been studied. Methods and results. 41 women suffering from arterial hypertension as well as 10 patients at risk of SCORE |
| Databáze: | Directory of Open Access Journals |
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