Elevation of Serum Prostate-Specific Antigen Levels in Males With Pulmonary Embolism

Autor: You-Fan Peng MD, PhD, Li-Ya Ma BS, Miao Luo BS
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Clinical and Applied Thrombosis/Hemostasis, Vol 30 (2024)
Druh dokumentu: article
ISSN: 1938-2723
10760296
DOI: 10.1177/10760296241250002
Popis: Hypoxemia is a clinical characteristic of pulmonary embolism (PE). Hypoxemia is associated with variations in serum prostate-specific antigen (PSA) levels. Thus, the present study aimed to determine serum PSA levels in patients with PE, which may be helpful in improving clinical evaluation in screening for prostate diseases in those with PE. Clinical data from 61 consecutive male patients with PE and 113 age-matched healthy male controls were retrospectively analyzed. The pulmonary artery obstruction index (PAOI) was used to evaluate the pulmonary embolic burden. Compared with healthy controls, serum total PSA (tPSA) levels were significantly increased ( P = .003), and free PSA (fPSA)/tPSA ratio was significantly decreased in patients with PE ( P
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