| Autor: |
Jean Marc Pujo, Dewi Yunia Fitriani, Hajer Ben Saad, Marwa Ghariani, Amel Dghim, Manel Mellouli, Antoine Burin, Remi Mutricy, Stephanie Houcke, Ariane Roujansky, Muchtaruddin Mansyur, Flaubert Nkontcho, Bertrand de Toffol, Ibtissem Ben Amara, Hatem Kallel |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Frontiers in Behavioral Neuroscience, Vol 17 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1662-5153 |
| DOI: |
10.3389/fnbeh.2023.1288814 |
| Popis: |
IntroductionStress exposure is a significant concern in the healthcare sector. This animal model study aims to reproduce caregivers’ working conditions and determine their impact on the brain.MethodTwenty-four healthy male rats of the Wistar strain were divided into four groups. Three groups were submitted each to one stressor for 21 days, while the fourth group was used as a control. Stressors were food and water deprivation (FW), permanent illumination (PI), and forced swimming (FS). At the end of the experiment, rats were euthanized, and stress biomarkers, biological parameters, and DNA damage were measured.ResultsProoxidant biomarker rates increased in the different groups (+50 to +75%) compared to the control (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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