Unexpected Vision Loss following Six Intravitreal Injections for Neovascular Age-Related Macular Degeneration

Autor: Maggie Hui, Robert Gunzenhauser, Alexander Dillon, Irena Tsui
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Case Reports in Ophthalmology, Vol 15, Iss 1, Pp 525-531 (2024)
Druh dokumentu: article
ISSN: 1663-2699
DOI: 10.1159/000537777
Popis: Introduction: We present a case of a patient with preceding vitreomacular traction (VMT) who developed a full-thickness macular hole (FTMH) following his sixth intravitreal aflibercept injection for the treatment of age-related macular degeneration and review the literature on risk factors and pathogenesis of this adverse event. Case Presentation: FTMH can occur after an extended number of repeat intravitreal injections in the setting of worsening vitreomacular adhesion or VMT. This patient’s FTMH was successfully treated surgically in a timely manner, and additional injections were resumed safely. Conclusions: Patients with an unexpected decrease in vision after intravitreal injections should be reevaluated with optical coherence tomography to rule out alternative pathology including vitreomacular interface abnormalities. FTMH, if present, should be treated promptly to allow for resumption of therapy as needed and visual optimization.
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