Autor: |
Yan-Long Ren, Tao-Tao Li, Wei Cui, Li-Min Zhao, Na Gao, Hua Liao, Jiang-Hui Zhang, Jun-Ming Zhu, Zhi-Yu Qiao, Shi-Chao Guo, Li-Li Pan |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) |
Druh dokumentu: |
article |
ISSN: |
2045-2322 |
DOI: |
10.1038/s41598-021-96632-w |
Popis: |
Abstract Interferon-gamma (IFN-γ) is a cytokine involved in the pathogenesis of Takayasu’s arteritis (TAK). However, the source of IFN-γ in TAK patients is not fully clear. We aimed to investigate the source of IFN-γ in TAK. 60 TAK patients and 35 health controls were enrolled. The lymphocyte subsets of peripheral blood were detected by flow cytometry, cytokines were detected by Bio-plex. The correlation among lymphocyte subsets, cytokines and disease activity indexes was analyzed by person correlation. The level of serum IFN-γ in TAK patients was significantly increased (P |
Databáze: |
Directory of Open Access Journals |
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