Outcomes and risks in palliative pancreatic surgery: an analysis of the German StuDoQ|Pancreas registry

Autor: Felix O. Hofmann, Rainer C. Miksch, Maximilian Weniger, Tobias Keck, Matthias Anthuber, Helmut Witzigmann, Natascha C. Nuessler, Christoph Reissfelder, Jörg Köninger, Michael Ghadimi, Detlef K. Bartsch, Werner Hartwig, Martin K. Angele, Jan G. D’Haese, Jens Werner
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Surgery, Vol 22, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 1471-2482
DOI: 10.1186/s12893-022-01833-3
Popis: Abstract Background Non-resectability is common in patients with pancreatic ductal adenocarcinoma (PDAC) due to local invasion or distant metastases. Then, biliary or gastroenteric bypasses or both are often established despite associated morbidity and mortality. The current study explores outcomes after palliative bypass surgery in patients with non-resectable PDAC. Methods From the prospectively maintained German StuDoQ|Pancreas registry, all patients with histopathologically confirmed PDAC who underwent non-resective pancreatic surgery between 2013 and 2018 were retrospectively identified, and the influence of the surgical procedure on morbidity and mortality was analyzed. Results Of 389 included patients, 127 (32.6%) underwent explorative surgery only, and a biliary, gastroenteric or double bypass was established in 92 (23.7%), 65 (16.7%) and 105 (27.0%). After exploration only, patients had a significantly shorter stay in the intensive care unit (mean 0.5 days [SD 1.7] vs. 1.9 [3.6], 2.0 [2.8] or 2.1 [2.8]; P
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