| Autor: |
J R Gilbertson, R A Gelman, T H Chiu, L I Gilbertson, T E Knauer |
| Jazyk: |
angličtina |
| Rok vydání: |
1978 |
| Předmět: |
|
| Zdroj: |
Journal of Lipid Research, Vol 19, Iss 6, Pp 757-762 (1978) |
| Druh dokumentu: |
article |
| ISSN: |
0022-2275 |
| DOI: |
10.1016/S0022-2275(20)41277-5 |
| Popis: |
Primary alcohols occur as trace lipids and are the only long-chain alcohol species present in Clostridium butyricum. Secondary alcohols do not occur physiologically in this microorganism. Exposure of these cells to the methyl ketone, pentadecan-2-one, results in a marked decrease in the primary alcohol content with the secondary alcohol, pentadadecan-2-ol, becoming the major alcohol present. This change in lipid composition is associated with a significant decrease in growth rate that is proportional to the log of the pentadecan 2-one concentration of the incubation medium. When these cells are incubated with pentadecan-2-ol alone, growth is unaffected. Simultaneous exposure of the bacteria to pentadecan-2-one and a mixture of primary alcohols results in a partial relief of the growth inhibition observed with the ketone alone. These observations indicate that pentadecan-2-one inhibits the formation of primary alcohols that are important for normal growth of this bacterium. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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