A large Venous-Arterial PCO2 Is Associated with Poor Outcomes in Surgical Patients
| Autor: | João M. Silva, Amanda M. Ribas R. Oliveira, Juliano Lopes Segura, Marcel Henrique Ribeiro, Carolina Nacevicius Sposito, Diogo O. Toledo, Ederlon Rezende, Luiz M. Sá Malbouisson |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Anesthesiology Research and Practice, Vol 2011 (2011) |
| Druh dokumentu: | article |
| ISSN: | 1687-6962 1687-6970 |
| DOI: | 10.1155/2011/759792 |
| Popis: | Background. This study evaluated whether large venous-arterial CO2 gap (PCO2 gap) preoperatively is associated to poor outcome. Method. Prospective study which included adult high-risk surgical patients. The patients were pooled into two groups: wide [P(v-a)CO2] versus narrow [P(v-a)CO2]. In order to determine the best value to discriminate hospital mortality, it was applied a ROC (receiver operating characteristic) curve for the [P(v-a)CO2] values collected preoperatively, and the most accurate value was chosen as cut-off to define the groups. Results. The study included 66 patients. The [P(v-a)CO2] value preoperatively that best discriminated hospital mortality was 5.0 mmHg, area=0.73. Preoperative patients with [P(v-a)CO2] more than 5.0 mmHg presented a higher hospital mortality (36.4% versus 4.5% P=0.004), higher prevalence of circulatory shock (56.8% versus 22.7% P=0.01) and acute renal failure postoperatively (27.3% versus 4.5% P=0.02), and longer hospital length of stays 20.0 (14.0–30.0) versus 13.5 (9.0–25.0) days P=0.01. Conclusions. The PCO2 gap values more than 5.0 mmHg preoperatively were associated with worse postoperatively outcome. |
| Databáze: | Directory of Open Access Journals |
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