Radiomics-based discrimination of coronary chronic total occlusion and subtotal occlusion on coronary computed tomography angiography

Autor: Jun Li, Lichen Ren, Hehe Guo, Haibo Yang, Jingjing Cui, Yonggao Zhang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Medical Imaging, Vol 24, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1471-2342
DOI: 10.1186/s12880-024-01248-x
Popis: Abstract Objectives Differentiating chronic total occlusion (CTO) from subtotal occlusion (SO) is often difficult to make from coronary computed tomography angiography (CCTA). We developed a CCTA-based radiomics model to differentiate CTO and SO. Methods A total of 66 patients with SO underwent CCTA before invasive angiography and were matched to 66 patients with CTO. Comprehensive imaging analysis was conducted for all lesioned vessels, involving the automatic identification of the lumen within the occluded segment and extraction of 1,904 radiomics features. Radiomics models were then constructed to assess the discriminative value of these features in distinguishing CTO from SO. External validation of the model was performed using data from another medical center. Results Compared to SO patients, CTO patients had more blunt stumps (internal: 53/66 (80.3%) vs. 39/66 (59.1%); external: 36/50 (72.0%) vs. 20/50 (40.0%), both p
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