| Autor: |
Laurence Fayol, Jilnar Yaacoub, Marine Baillat, Clotilde des Robert, Vanessa Pauly, Gina Dagau, Julie Berbis, Frédérique Arnaud, Audrey Baudesson, Véronique Brévaut-Malaty, Justine Derain-Court, Blandine Desse, Clara Fortier, Eric Mallet, Anaïs Ledoyen, Christelle Parache, Jean-Claude Picaud, Philippe Quetin, Bénédicte Richard, Anne-Marie Zoccarato, Anne-Marie Maillotte, Farid Boubred |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Nutrients, Vol 16, Iss 9, p 1292 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2072-6643 |
| DOI: |
10.3390/nu16091292 |
| Popis: |
In preterm infants, early nutrient intake during the first week of life often depends on parenteral nutrition. This study aimed to evaluate the influence of standardized parenteral nutrition using three-in-one double-chamber solutions (3-in-1 STD-PN) on early neonatal growth in a cohort of moderately preterm (MP) infants. This population-based, observational cohort study included preterm infants admitted to neonatal centers in the southeast regional perinatal network in France. During the study period, 315 MP infants with gestational ages between 320/7 and 346/7 weeks who required parenteral nutrition from birth until day-of-life 3 (DoL3) were included; 178 received 3-in-1 STD-PN solution (56.5%). Multivariate regression was used to assess the factors associated with the relative body-weight difference between days 1 and 7 (RBWD DoL1-7). Infants receiving 3-in-1 STD-PN lost 36% less body weight during the first week of life, with median RBWD DoL1-7 of −2.5% vs. −3.9% in infants receiving other PN solutions (p < 0.05). They also received higher parenteral energy and protein intakes during the overall first week, with 85% (p < 0.0001) and 27% (p < 0.0001) more energy and protein on DoL 3. After adjusting for confounding factors, RBWD DoL1-7 was significantly lower in the 3-in-1 STD-NP group than in their counterparts, with beta (standard deviation) = 2.08 (0.91), p = 0.02. The use of 3-in-1 STD-PN provided better energy and protein intake and limited early weight loss in MP infants. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
