Hiperglicemia na intoxicação escorpiônica experimental em cão

Autor: Lineu Freire-Maia, Marcelo Carvalho Ferreira, Carlos Gomes da Silva
Jazyk: angličtina
Rok vydání: 1959
Předmět:
Zdroj: Memorias do Instituto Oswaldo Cruz, Vol 57, Iss 1, Pp 105-114 (1959)
Druh dokumentu: article
ISSN: 0074-0276
1678-8060
DOI: 10.1590/S0074-02761959000100008
Popis: The production of hyperglycemia during the acute phase of scorpion poisoning produced by T. bahiensis in dogs is confirmed now. The highest degree on average, was reached 10 minutes after the injection of venom. In our hands, the previous bilateral adrenalectomy did not avoid the hyperglycemia. The average of the blood sugar level has been similar to that observed in dogs with adrenal glands, the highest blood sugar level was also registered after 10 minutes. The hyperglycemia obtained in adrenolectomized dogs is, probably, due to the liberation of Sympatin (Nor-adrenalin and adrenalin) as a consequence of the central excitation by the poison on the hepatic nerves and other ganglionar terminations of the Sympathetic Nervous System. Our present researches suggest that the venom has adrenergic action besides the central action.
Databáze: Directory of Open Access Journals