Clinical use of anti-histone antibodies in idiopathic and drug-induced lupus

Autor:	Adrian Y. S. Lee
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Anti-histone antibodies autoantibodies drug-induced lupus histone systemic lupus erythematosus Immunologic diseases. Allergy RC581-607
Zdroj:	Immunological Medicine, Vol 45, Iss 4, Pp 180-185 (2022)
Druh dokumentu:	article
ISSN:	25785826 2578-5826
DOI:	10.1080/25785826.2022.2060168
Popis:	AbstractAnti-histone antibodies (AHAs) make their appearance in a number of systemic autoimmune diseases including systemic lupus erythematosus (SLE) and drug-induced lupus erythematosus (DILE). Although being known for over 50 years, they are poorly studied and understood. There is emerging evidence for their use in predicting clinical features of SLE, diversifying their clinical use. AHAs, however, are probably less prevalent in DILE than once thought owing to a move away from older DILE drugs to modern biological agents which do not appear to elicit AHAs. This review examines the historical studies that have defined AHAs and looks at some of the recent work with these autoantibodies.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/836d931c714f4406a24b24eebb5e2df9 Zobrazit plný text záznamu View record in DOAJ