The prevalence and factors associated with coronary heart disease in patients with gout

Autor: E. I. Markelova, M. S. Eliseev, E. V. Ilinykh, D. E. Karateev, S. I. Gluhova, E. L. Nasonov
Jazyk: ruština
Rok vydání: 2023
Předmět:
Zdroj: Научно-практическая ревматология, Vol 61, Iss 5, Pp 562-568 (2023)
Druh dokumentu: article
ISSN: 1995-4484
1995-4492
DOI: 10.47360/1995-4484-2023-562-568
Popis: Background. Gout is associated with increased risk of cardiovascular disease (CVD) morbidity and mortality. Therefore, an association between coronary heart disease (CHD) and gout deserves careful examination. The aim of this study was to determine the prevalence of CHD and factors associated with CHD in patients (pts) with gout. Methods. 286 male patients with gout were included; age – 51.2 [42.8; 59.4] years (ys), disease duration – 6.2 [3.8; 12.1] ys. All patients underwent standard clinical examination, screening traditional risk factors (TRF) of CVD. We estimated the adjusted odds ratio (OR) and 95% confidence interval (95% CI). Results. CHD was found in 111 out of the 286 pts (38.8%), MI had a history in 29.7%. Compared to individuals with CHD, participants without CHD were older (56.7 [52.1; 61.1] vs 46.2 [40.6; 53.4] ys), had longer duration of gout (9.3 [4.7; 15.1] vs 5.6 [3.3; 9.7] ys) (for all p
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