Mechanical Characterization for Cellular Mechanobiology: Current Trends and Future Prospects

Autor: Badri Narayanan Narasimhan, Matthew S. Ting, Tarek Kollmetz, Matthew S. Horrocks, Anaïs E. Chalard, Jenny Malmström
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Druh dokumentu: article
ISSN: 2296-4185
DOI: 10.3389/fbioe.2020.595978
Popis: Accurate mechanical characterization of adherent cells and their substrates is important for understanding the influence of mechanical properties on cells themselves. Recent mechanobiology studies outline the importance of mechanical parameters, such as stress relaxation and strain stiffening on the behavior of cells. Numerous techniques exist for probing mechanical properties and it is vital to understand the benefits of each technique and how they relate to each other. This mini review aims to guide the reader through the toolbox of mechanical characterization techniques by presenting well-established and emerging methods currently used to assess mechanical properties of substrates and cells.
Databáze: Directory of Open Access Journals