EFFECT OF DIFFERENT DOSES OF PUMPKIN SEED OIL AS AN ANTI-INFLAMMATORY AND ANALGESIC ON MICE

Autor: N. Z. yahya
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: The Iraqi Journal of Agricultural science, Vol 51, Iss 2 (2020)
Druh dokumentu: article
ISSN: 0075-0530
2410-0862
DOI: 10.36103/ijas.v51i2.998
Popis: To evaluate the role of anti-inflammatory and analgesicof Iraqi pumpkin seed oil. The oil seed (25-100 mg / kg) were investigated using various experimental models for analgesic and anti-inflammatory benefit. Acetic acid and thermal induced models of pain were used to examine the anti-nociceptive property. Though models of oedema induced by carragenin were used to evaluate anti-inflammation. Results were reported from these studies that the extract prepared from Iraqi pumpkin seeds possess potential anti-inflammatory and analgesic activity when compared with standard drug Diclofenac. Even though all the concentrations showed varying degree of inflammatory and analgesic activity, 100mg/kg bw showed better anti inflammatory and analgesic activity
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