Hepatitis B virus-related post-infectious glomerulonephritis: a case report

Autor: Mohamed Arrayhani, Fatima Zahra Batta, Souad Dahri, Randa El Youbi, Nourdin Aqodad, Tarik Sqalli
Jazyk: English<br />French
Rok vydání: 2013
Předmět:
Zdroj: The Pan African Medical Journal, Vol 16, Iss 78 (2013)
Druh dokumentu: article
ISSN: 1937-8688
DOI: 10.11604/pamj.2013.16.78.2312
Popis: Hepatitis B virus infection is an uncommon cause of acute glomerulonephritis. We present a case of acute glomerulonephritis revealing a chronic viral hepatitis B. A 45 year-old man was admitted in the nephrology department of Hassan II university hospital (Fez, Morocco) for nephritic syndrome with advanced acute kidney injury. The investigations have revealed viral hepatitis B with a positive HBV-DNA and Others viral serology tests were negative. Renal biopsy showed a diffuse and global endocapillary proliferation without extra-capillary proliferation; and global deposits of C3 and Ig G On immunofluorescence. There wasn't any other infectious cause. We thus retained the diagnosis of hepatitis B virus-associated acute glomerulonephritis. He was given entecavir and corticosteroids. Three months later, the evolution was marked by the normalization of renal function, negativity of proteinuria and HBV DNA became undetectable. There was no relapse of glomerulonephritis and HBV viral load was still negative after one year follow-up.
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