Non-alcoholic fatty liver disease: the pathologist’s perspective

Autor:	Wei-Qiang Leow, Anthony Wing-Hung Chan, Paulo Giovanni L. Mendoza, Regina Lo, Kihan Yap, Haeryoung Kim
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	non-alcoholic fatty liver disease biopsy diagnosis prognosis histology Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Clinical and Molecular Hepatology, Vol 29, Iss Suppl, Pp S302-S318 (2023)
Druh dokumentu:	article
ISSN:	2287-2728 2287-285X
DOI:	10.3350/cmh.2022.0329
Popis:	Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases characterized by fatty accumulation in hepatocytes, ranging from steatosis, non-alcoholic steatohepatitis, to cirrhosis. While histopathological evaluation of liver biopsies plays a central role in the diagnosis of NAFLD, limitations such as the problem of interobserver variability still exist and active research is underway to improve the diagnostic utility of liver biopsies. In this article, we provide a comprehensive overview of the histopathological features of NAFLD, the current grading and staging systems, and discuss the present and future roles of liver biopsies in the diagnosis and prognostication of NAFLD.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/832d4fc2c32140bc8b522cee9129c2bb Zobrazit plný text záznamu View record in DOAJ