| Autor: |
Marisela Hernandez-Santillan, Moisés Martínez-Castillo, Zaira Medina-Ávila, Abigail Hernández-Barragan, María Lemus-Peña, Daniel Montes de Oca-Ángeles, José Luis Pérez-Hernández, Fátima Higuera-De la Tijera, Daniel Santana-Vargas, Eduardo Montalvo-Jave, Paula Cordero-Pérez, Linda Muñoz-Espinoza, Jacqueline Córdova-Gallardo, Aldo Torre-Delgadillo, Gabriela Gutiérrez-Reyes |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Annals of Hepatology, Vol 28, Iss , Pp 100949- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1665-2681 |
| DOI: |
10.1016/j.aohep.2023.100949 |
| Popis: |
Introduction and Objectives: Chronic liver diseases are characterized by persistent inflammation related to high production of cytokines such as IL-12 and chemokine CXCL-10/IP-10 that attract activated Th1 lymphocytes that increase the production of IFN-g and TNF-a, perpetuating the inflammatory cascade. This study aimed to compare serum levels of IL-12 and CXCL-10 in different etiologies of liver disease. Materials and Methods: A cross-sectional and multicenter study was carried out, including subjects with alcoholism according to criteria WHO, without (OH) and with liver injury (cirrhosis, CiOH) and (Alcoholic Hepatitis, HA); non-alcoholic fatty liver (NAFLD) and chronic Hepatitis C (CHC), diagnosed by clinical, biochemical data. They were compared with control subjects (CT). For determination of IL-12 and CXCL-10 with Multiplex®-MERCK©. Statistical analysis by SPSS V.22 using U de Mann Whitney, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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