Pubertal stage, sex and behaviour in neurodevelopmental disorders versus typical development: a cross-sectional study
| Autor: | Stelios Georgiades, Muhammad Ayub, Robert Nicolson, Russell Schachar, Annie Dupuis, Melanie Penner, Paul Arnold, Jennifer Crosbie, Elizabeth Kelley, Evdokia Anagnostou |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | BMJ Paediatrics Open, Vol 6, Iss 1 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2022-0014 2399-9772 |
| DOI: | 10.1136/bmjpo-2022-001469 |
| Popis: | Objective To determine the association between pubertal stage, sex and behavioural profile across and within neurodevelopmental disorders (NDDs) compared with typically developing (TD) youth.Methods This was a cross-sectional study from the Province of Ontario Neurodevelopmental Disorders network, including children/youth with various NDDs and TD controls. Caregivers completed the Child Behavior Checklist (CBCL). Participants were grouped into three puberty stages: prepuberty (Tanner stage 1), early puberty (Tanner stages 2–3) and late puberty (Tanner stages 4–5). The association between pubertal stage and CBCL scores was assessed controlling for sex and diagnosis.Results The analysis included 1043 participants (male=733; 70.3%). A three-way interaction between pubertal status, sex and diagnosis was not significant for internalising or externalising behaviour. Diagnosis was significantly associated with CBCL scores for both internalising (p |
| Databáze: | Directory of Open Access Journals |
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